Is there any oral medication for plantar warts?

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Because a plantar wart is a manifestation of a virus, there is no medication to eliminate it. Viruses typically are left to run their course. Just like a cold, you don't treat the virus itself, but you do treat the symptoms.

There are some who believe that oral cimetidine, commonly known as the heartburn medication Tagamet, will help to eliminate warts. It is reported that there is some slow success in children, but most don't use it as a primary treatment Instead, it is used if there is a widespread infection of warts while other treatments are being used as well.
Dr. Andrew Schneider
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A podiatrist and foot surgeon in Houston, TX.